University of Wisconsin–Madison

Research & Updates

Ellipsoid Zone Status in Eyes with Retinal Vein Occlusion in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2) (2019)

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Chandana Papudesu, Amitha Domalpally, Neal Oden, Paul Van Veldhuisen, Ingrid U. Scott, Michael S. Ip, Barbara A. Blodi Abstract Purpose: To evaluate the status of the ellipsoid zone (EZ) assessed by spectral domain optical coherence tomography (SDOCT) and its association with visual acuity (VA) in eyes with macular edema secondary to central or hemiretinal vein …

Comparison of Diabetic Retinopathy Severity Level Assessment Between Standard 7-field Imaging and Ultrawide Field Color Imaging (2019)

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Kristi Dohm, Nancy Barrett, Kyle McDaniel, Barbara Blodi, Amitha Domalpally Abstract Purpose: Diabetic retinopathy has traditionally been evaluated using the Early Treatment Diabetic Retinopathy Severity Scale (ETDRS) from 7-field (7F) stereoscopic color photographs and is considered the gold standard. Ultrawide field color (UWF-C) imaging has recently become available for viewing a wider area of the …

Characteristics of Reticular Pseudodrusen in AREDS2 (2019)

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Meghana Agni, Jeong W. Pak, Amitha Domalpally, Emily Y. Chew Abstract Purpose: To assess the correlation between peripheral non-perfusion from ultrawide field fluorescein angiography (UWF FA) and Early Treatment Diabetic Retinopathy Severity (ETDRS) level from color fundus photographs (FP) of eyes with diabetic retinopathy (DR). Methods: Capillary non-perfusion was evaluated from UWF FA (Optos) images …

Correlation of peripheral non-perfusion from ultrawide field fluorescein angiography to color ETDRS severity level in eyes with diabetic retinopathy (2019)

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Ellie Corkery, Kyle McDaniel, Amitha Domalpally, Barbara Blodi Abstract Purpose: To assess the correlation between peripheral non-perfusion from ultrawide field fluorescein angiography (UWF FA) and Early Treatment Diabetic Retinopathy Severity (ETDRS) level from color fundus photographs (FP) of eyes with diabetic retinopathy (DR). Methods: Capillary non-perfusion was evaluated from UWF FA (Optos) images in three …

Comparable Growth Rates of Bilateral Geographic Atrophy due to Age-related Macular Degeneration (2019)

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Jeong W. Pak, Amitha Domalpally, Kyle McDaniel, Barbara Blodi Abstract Purpose: To evaluate growth rate and characteristics of bilateral geographic atrophy (GA) associated with age-related macular degeneration (AMD) from fundus color and autofluorescence images Methods: We evaluated fundus photographs (FP) and autofluorescence images (AF) in AMD patients with bilateral GA at baseline and 1 year …

Utility of Ultra-Widefield Imaging in Patients with Inherited Retinal Diseases (2019)

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Rachael Lyerla, Nickie Stangel, Angie Adler, Kevin Vo, Melanie Schmitt, Kimberly Stepien Abstract Purpose: With emerging therapies underway for Inherited Retinal Diseases (IRDs), better documentation and qualitative assessment of peripheral retinal findings in these unique eyes may facilitate more accurate disease assessment and prove useful in potential therapeutic interventions. Here we performed a retrospective, observational …

Fundus AutoFluorescence Risk Factors for Progression of Geographic Atrophy in the Age-Related Eye Disease Study 2 (2018)

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Jeong W. Pak, Amitha Domalpally, Elivira Agron, Ronald Danis, Traci E. Clemons, Emily Y. Chew, and the AREDS2 Research Group Abstract Purpose: To identify risk factors for progression of geographic atrophy (GA) from autofluoresence (AF) images in eyes with age-related macular degeneration (AMD) Methods: AF images from the Age-Related Eye Disease Study 2 (AREDS2) ancillary …

Correlation of Optical Coherence Tomography Angiography Vascular Density to Color ETDRS Severity Level in Eyes with Diabetic Retinopathy (2018)

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Ellie Corkery, Amitha Domalpally, Dawn Myers, Jeong W. Pak, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy severity is evaluated using color fundus photographs (FP) employing the Early Treatment Diabetic Retinopathy Severity (ETDRS) scale. Optical Coherence Tomography Angiography (OCTA) is a recently developed imaging technique that generates volumetric angiography including an enface view of the …

Comparison of Foveal Avascular Zone Metrics in Diabetic Retinopathy (2018)

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Kimberly Stepien, Ellie Corkery, Sheila Watson, Cynthia Hurtenbach, Ralph Trane, Jeong Won Pak, Amitha Domalpally Abstract Purpose: Foveal avascular zone (FAZ) abnormalities are known in diabetic retinopathy (DR) and may prove useful as a biomarker in DR diagnosis and management. Fundus photography and fluorescein angiography (FA) as shown in the ETDRS are the gold standard …

Evaluation of Diabetic Retinopathy from UltraWide Field Color Photographs (2018)

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Nancy Barrett, Kristine Lang, Amitha Domalpally, Ellie Corkery, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy (DR) has traditionally been evaluated using Early Treatment Diabetic Retinopathy Study (ETDRS) levels from stereoscopic 7 field color photographs. The UltraWide field (UWF) images (Optos, Inc) provide a view much beyond the standard 7 field images. We assessed the …