Ronald P. Danis, Amitha Domalpally, Ellie Corkery, Ruth Shaw, Ashwini Narkar, Jim White Abstract Purpose: Given that baseline area and configuration of GA are associated with its progression rate, we hypothesized that a non circular configuration has a higher growth rate. Index of non circularity was developed on color photographs and was a strong predictor …
Jeong W. Pak, Amitha Domalpally, Dawn Myers, Xiufen Yang, Ashwini Narkar, Yijun Huang, and Ronald P. Danis Abstract Purpose: To characterize drusen morphology and retinal layer abnormalities by simple, ordinal description and to associate these features with drusen progression over one year on SD-OCT scans. Methods: Twenty two pairs of SD-OCT macular volume scans at …
Ronald P. Danis, Amitha Domalpally, Larry D. Hubbard, Ashwini Narkar, James White, Emily Chew, Traci Clemons Abstract Purpose: We evaluated a parameter based upon an indirect measure of the extent to which the shape of an area of GA in an eye departs from that of a circle as a risk factor for rate of …
Amitha Domalpally, Ronald P Danis, Ashwini Narkar, Barbara A. Blodi, Emily Chew, Traci Clemons Abstract Purpose: To evaluate the features associated with progression of Geographic Atrophy (GA) from Autofluorescence (AF) images. Methods: AF images (from scanning laser ophthalmoscopy) images are captured at annual visits in the Age Related Eye Disease Study 2 (AREDS2) ancillary study. …
Dawn Myers, Amitha Domalpally, Jill C. Kubiak, Qian Peng, Ronald P. Danis Abstract Purpose: The outer boundary line (BL) location differs among SDOCT vendors making it difficult to compare retinal thickness data in clinical trials. No automated software is commercially available that can segment a common BL from all SDOCT types. Manual segmentation of BLs …
Larry D. Hubbard, Qian Peng, Wanjie Sun, Sapna Gangaputra, Patricia A. Cleary, Charles S. Chandler, Thomas W. Pauli, Ronald P. Danis, and the DCCT/EDIC Study Group Abstract Purpose: To explore associations of retinal arteriolar and venular caliber with diabetic retinopathy (DR) in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications Study …
James L. Reimers, Sapna Gangaputra, Barbara Esser, Trina M. Harding, Qian Peng, Ronald P. Danis, Larry D. Hubbard, and the DCCT/EDIC Study Group Abstract Purpose: To evaluate diabetic macular edema (DME) levels from green channel (GrCh) fundus images (simulating red free) as compared to full color (Red/Green/Blue, RGB) images. Methods: From the Diabetes Control and …
Sapna Gangaputra, Ronald Danis, and Talat Almukhtar for the Diabetic Retinopathy Clinical Research Network. Department of Ophthalmology, University of Wisconsin, Madison, WI. Jaeb Center for Health Research, Tampa, FL. Abstract Purpose: To compare grading of diabetic retinopathy of film versus digital images from a subset of Diabetic Retinopathy Clinical Research Network (DRCR.net) clinical centers. Methods: …
James L Reimers, Sapna Gangaputra, Barbara A. Esser, Trina M. Harding, DW Thayer, Qian Peng, Larry D. Hubbard , Ronald P. Danis Abstract Purpose: To compare diabetic retinopathy (DR) severity levels from green channel (GrCh) fundus images (simulating red free) with full color (Red/Green/Blue) images. Methods: From the Diabetes Control and Complications Trial/Epidemiology of Diabetes …
Susan Reed, Sapna Gangaputra, Amitha Domalpally, Qian Peng, Michael Altaweel, and the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group Abstract Purpose: To describe the uveitis grading program and report the reproducibility of evaluation procedures for color fundus images in the MUST Trial. The MUST trial is the first large multi-center randomized clinical trial comparing …