University of Wisconsin–Madison

Research & Updates

Association of Outer Retinal Layer Morphology with Visual Acuity in Patients with Macular Edema Secondary to Retinal Vein Occlusion – A SCORE Study Ancillary Study (2010)

Posted on

Amitha Domalpally, Qian Daisy Peng, Ronald P Danis, Barbara Blodi, Ingrid U Scott, Michael Ip, and SCORE Study Research Group Abstract Purpose: To evaluate the relationship between outer retinal morphology assessed by optical coherence tomography (OCT) and visual acuity (VA) in patients with macular edema secondary to retinal vein occlusion. Methods: High resolution cross hair …

Evaluation of 4 Wide Digital Images for Diabetic Retinopathy (2010)

Posted on

Trina M. Harding, Sapna Gangaputra, James L. Reimers, Qian Peng, Ronald P. Danis Abstract Purpose: The 4 Wide Angle Fields (4W) Digital fundus imaging protocol is designed to capture approximately the same retinal area as the ETDRS 7 modified fields (7M) protocol, but with fewer images. We sought to evaluate the grading procedure and reproducibility …

Evaluation of Precursors of Geographic Atrophy associated with Age-Related MMacular Degeneration (AMD) in the Age-Related Eye Disease Study 2 (AREDS2) (2010)

Posted on

Jane R. Armstrong, James White, Amitha Domalpally, Ronald P. Danis, Barbara Blodi, Qian Peng, Michael L. Klein, AREDS2 Research Group. Abstract Purpose: To assess retinal precursors of Geographic atrophy (GA) in digital images from the AREDS2 data set. Methods: The Age Related Eye Disease Study 2 (AREDS2) is a multi-center randomized trial of 4,200 participants …

Reproducibilty of Classification by AREDS Severity Scale and Component Features in AREDS2 (2009)

Posted on

Ronald P. Danis, Jane Armstrong, Qian Peng, Amitha Domalpally, Larry Hubbard, and the AREDS2 Research Group Abstract Purpose: The 11-step AREDS Severity Scale for age related macular degeneration (AMD) cross tabulates macular features from stereoscopic color photographs (AREDS Report no. 18) according to the risk of progression to advanced AMD. Two-step progression along this scale …

Rationale and Transition from Multistep Grading to Single Step Grading of Retinal Images at a Reading Center (2009)

Posted on

Qian Peng, Ronald P. Danis, Amitha Domalpally, Larry Hubbard, Jane Armstrong, and the AREDS2 Research Group Abstract Purpose: In the Age-Related Eye Disease Study 2 (AREDS2), a large multicenter clinical trial of nutritional supplements on the progression of age-related macular degeneration (AMD), we describe the rationale to migrate from the traditional multistep grading system (MS) …

Calcified Drusen as a Baseline Risk Factor for Progression to Advanced Age-Related Macular Degeneration from the Age-Related Eye Disease Study (2006)

Posted on

Jane Armstrong, Ronald Danis, Matthew D. Davis , B. Zhang, L. –Y. Lee, Ronald Klein, Barbara E. Klein, Larry D. Hubbard Abstract Purpose: To analyze the presence of calcified drusen as a baseline risk factor for progression to advanced AMD, and to illustrate the course of such eyes, in the Age-Related Eye Diseases Study (AREDS). …

Diameter/Area of the Standardized Optic Disc and Accurate Scaling in Retinal Images (2005)

Posted on

J.A. Elledge, M.D. Davis, Larry D. Hubbard, James L. Reimers, C.A. Fink, D.G. Hafford, R.A. Susman Abstract Purpose: To compare classic and modern assumptions regarding disc dimensions, as documented in fundus photos, and explore their impact on linear and area measurements of abnormalities. To investigate distance from disc center to macular center (D-M) as a …

Illustration of the AMD Severity Scale from the Age-Related Eye Diseases Study (2004)

Posted on

Jane Armstrong, Matthew D. Davis, R.E. Gangnon, L. –Y. Lee, Ronald Klein, Barbara E. Klein, R. C. Milton, F.L. Ferris, Larry D. Hubbard Abstract Purpose: To summarize the AREDS severity scale for age–related macular degeneration (AMD) and to present photographs of typical eyes from each level. Methods: AREDS enrolled persons without advanced AMD in at …