Jeong W. Pak, Amitha Domalpally, Elivira Agron, Ronald Danis, Traci E. Clemons, Emily Y. Chew, and the AREDS2 Research Group Abstract Purpose: To identify risk factors for progression of geographic atrophy (GA) from autofluoresence (AF) images in eyes with age-related macular degeneration (AMD) Methods: AF images from the Age-Related Eye Disease Study 2 (AREDS2) ancillary …
Ellie Corkery, Amitha Domalpally, Dawn Myers, Jeong W. Pak, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy severity is evaluated using color fundus photographs (FP) employing the Early Treatment Diabetic Retinopathy Severity (ETDRS) scale. Optical Coherence Tomography Angiography (OCTA) is a recently developed imaging technique that generates volumetric angiography including an enface view of the …
Kimberly Stepien, Ellie Corkery, Sheila Watson, Cynthia Hurtenbach, Ralph Trane, Jeong Won Pak, Amitha Domalpally Abstract Purpose: Foveal avascular zone (FAZ) abnormalities are known in diabetic retinopathy (DR) and may prove useful as a biomarker in DR diagnosis and management. Fundus photography and fluorescein angiography (FA) as shown in the ETDRS are the gold standard …
Nancy Barrett, Kristine Lang, Amitha Domalpally, Ellie Corkery, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy (DR) has traditionally been evaluated using Early Treatment Diabetic Retinopathy Study (ETDRS) levels from stereoscopic 7 field color photographs. The UltraWide field (UWF) images (Optos, Inc) provide a view much beyond the standard 7 field images. We assessed the …
Mary K. Wilda, Ellie Corkery, Cynthia Hurtenbach, Amitha Domalpally, Ralph Trane, Barbara A. Blodi Abstract Purpose: Considered the gold standard in assessing location of choroidal neovascular (CNV) lesions, fluorescin angiography (FA) is the primary imaging modality used to determine CNV lesion eligibility in clinical trials. With structural spectral domain optical coherence tomography (SD-OCT), it is …
Amitha Domalpally, Ralph Trane, James Reimers, Barbara Blodi Abstract Purpose: The Early Treatment Diabetic Retinopathy Study (ETDRS) study established a 12 step scale to document the severity of diabetic retinopathy (DR) using 7 field stereoscopic color fundus photographs (CFP). The ETDRS scale is used as an outcome in clinical trials. We compared reproducibility in the …