University of Wisconsin–Madison

Tag: Key Posters

Correlation of Optical Coherence Tomography Angiography Vascular Density to Color ETDRS Severity Level in Eyes with Diabetic Retinopathy (2018)

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Ellie Corkery, Amitha Domalpally, Dawn Myers, Jeong W. Pak, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy severity is evaluated using color fundus photographs (FP) employing the Early Treatment Diabetic Retinopathy Severity (ETDRS) scale. Optical Coherence Tomography Angiography (OCTA) is a recently developed imaging technique that generates volumetric angiography including an enface view of the …

Comparison of Foveal Avascular Zone Metrics in Diabetic Retinopathy (2018)

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Kimberly Stepien, Ellie Corkery, Sheila Watson, Cynthia Hurtenbach, Ralph Trane, Jeong Won Pak, Amitha Domalpally Abstract Purpose: Foveal avascular zone (FAZ) abnormalities are known in diabetic retinopathy (DR) and may prove useful as a biomarker in DR diagnosis and management. Fundus photography and fluorescein angiography (FA) as shown in the ETDRS are the gold standard …

Evaluation of Diabetic Retinopathy from UltraWide Field Color Photographs (2018)

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Nancy Barrett, Kristine Lang, Amitha Domalpally, Ellie Corkery, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy (DR) has traditionally been evaluated using Early Treatment Diabetic Retinopathy Study (ETDRS) levels from stereoscopic 7 field color photographs. The UltraWide field (UWF) images (Optos, Inc) provide a view much beyond the standard 7 field images. We assessed the …

Agreement in CNV Lesion Location as Assessed by SD-OCT vs. Fluorescein Angiography (2018)

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Mary K. Wilda, Ellie Corkery, Cynthia Hurtenbach, Amitha Domalpally, Ralph Trane, Barbara A. Blodi Abstract Purpose: Considered the gold standard in assessing location of choroidal neovascular (CNV) lesions, fluorescin angiography (FA) is the primary imaging modality used to determine CNV lesion eligibility in clinical trials. With structural spectral domain optical coherence tomography (SD-OCT), it is …

Evaluation of Diabetic Retinopathy Using the ETDRS Severity Scale – Is There a Gold Standard? (2018)

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Amitha Domalpally, Ralph Trane, James Reimers, Barbara Blodi Abstract Purpose: The Early Treatment Diabetic Retinopathy Study (ETDRS) study established a 12 step scale to document the severity of diabetic retinopathy (DR) using 7 field stereoscopic color fundus photographs (CFP). The ETDRS scale is used as an outcome in clinical trials. We compared reproducibility in the …

Reading Center Measurement of Capillary Non-Perfusion Using Ultrawidefield (UWF) Fluorecein Angiography in Two Prospective Clinical Trials of Retinal Vein Occlusion and Diabetic Retinopathy (2017)

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Ellie Corkery, Amitha Domalpally, Ruth Shaw, Kelly Warren, Sheila Watson, Barbara Blodi Abstract Purpose: According to the October 2016 Report from the NEI/FDA Diabetic Retinopathy Clinical Trial Design and Endpoints workshop (Investigative Ophthalmology & Visual Science October 2016, Vol.57, 5127-5142.), “Change in retinal capillary nonperfusion area over time as measured with UWF fluorescein angiography to …

Standardization of OCT Derived Central Retinal Thickness with Custom Segmentation Software (2017)

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Gregory Sovinski, Amitha Domalpally, Dawn Myers, Yijun Huang, Barbara Blodi Abstract Purpose: Central Retinal Thickness (CRT) is a measure derived from Optical Coherence Tomography (OCT) scans and is an important outcome in clinical trials. Differences in segmentation algorithms among various commercial OCT machines leads to variability in CRT in the same eye and results in …

Drusen Area Measured from Color Photographs Compared to RPE and Drusen Volume from SD-OCT in Eyes with AMD over One Year (2017)

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Ronald P Danis, Amitha Domalpally, Ralph Trane, Jeong W Pak Abstract Purpose: To quantitatively evaluate the relationship between drusen area from photographs and drusen [a1.1]volume from SDOCT volume scans with respect to baseline association, AREDS Severity Scale, and change in these measurements over time. Methods: In a set of 88 eyes with non-advanced AMD (median …

Optical Coherence Tomography in the Evaluation of Neovascular Lesions and Serous Pigment Epithelial Detachments in Polypoidal Choroidal Vasculopathy (2016)

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Eric Weinlander, Amitha Domalpally, Ellie Corkery, Barbara Blodi Abstract Purpose: Spectral domain optical coherence tomography (SD-OCT) has not routinely been used to measure features of polypoidal choroidal vasculopathy (PCV) due to its anatomic complexity. We hypothesize that a novel algorithm-based semi-automated approach to grading SD-OCT will overcome this difficulty to yield reliable and accurate measurements …

Standardized Assessment of Drusen Measurements from SDOCT Scans in Dry Age Related Macular Degeneration (2015)

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Amitha Domalpally, Yijun Huang, Dawn Myers, Taylor Starnes, Zhe Liu, Ronald P. Danis, Barbara A. Blodi Abstract Purpose: To compare retinal pigment epithelium (RPE) and retinal thickness assessments made with SDOCTin eyes with dry AMD and normal eyes. Methods: Eyes with intermediate AMD or worse in participants between 50 – 85 years of age were …