Nancy Barrett, Kristine Lang, Amitha Domalpally, Ellie Corkery, Ralph Trane, Barbara Blodi Abstract Purpose: Diabetic retinopathy (DR) has traditionally been evaluated using Early Treatment Diabetic Retinopathy Study (ETDRS) levels from stereoscopic 7 field color photographs. The UltraWide field (UWF) images (Optos, Inc) provide a view much beyond the standard 7 field images. We assessed the …
Amitha Domalpally, Ralph Trane, James Reimers, Barbara Blodi Abstract Purpose: The Early Treatment Diabetic Retinopathy Study (ETDRS) study established a 12 step scale to document the severity of diabetic retinopathy (DR) using 7 field stereoscopic color fundus photographs (CFP). The ETDRS scale is used as an outcome in clinical trials. We compared reproducibility in the …
Ellie Corkery, Amitha Domalpally, Ruth Shaw, Kelly Warren, Sheila Watson, Barbara Blodi Abstract Purpose: According to the October 2016 Report from the NEI/FDA Diabetic Retinopathy Clinical Trial Design and Endpoints workshop (Investigative Ophthalmology & Visual Science October 2016, Vol.57, 5127-5142.), “Change in retinal capillary nonperfusion area over time as measured with UWF fluorescein angiography to …
Larry D. Hubbard, Qian Peng, Wanjie Sun, Sapna Gangaputra, Patricia A. Cleary, Charles S. Chandler, Thomas W. Pauli, Ronald P. Danis, and the DCCT/EDIC Study Group Abstract Purpose: To explore associations of retinal arteriolar and venular caliber with diabetic retinopathy (DR) in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications Study …
Sapna Gangaputra, Ronald Danis, and Talat Almukhtar for the Diabetic Retinopathy Clinical Research Network. Department of Ophthalmology, University of Wisconsin, Madison, WI. Jaeb Center for Health Research, Tampa, FL. Abstract Purpose: To compare grading of diabetic retinopathy of film versus digital images from a subset of Diabetic Retinopathy Clinical Research Network (DRCR.net) clinical centers. Methods: …
James L Reimers, Sapna Gangaputra, Barbara A. Esser, Trina M. Harding, DW Thayer, Qian Peng, Larry D. Hubbard , Ronald P. Danis Abstract Purpose: To compare diabetic retinopathy (DR) severity levels from green channel (GrCh) fundus images (simulating red free) with full color (Red/Green/Blue) images. Methods: From the Diabetes Control and Complications Trial/Epidemiology of Diabetes …
Trina M. Harding, Sapna Gangaputra, James L. Reimers, Qian Peng, Ronald P. Danis Abstract Purpose: The 4 Wide Angle Fields (4W) Digital fundus imaging protocol is designed to capture approximately the same retinal area as the ETDRS 7 modified fields (7M) protocol, but with fewer images. We sought to evaluate the grading procedure and reproducibility …