Amitha Domalpally, Yijun Huang, Dawn Myers, Taylor Starnes, Zhe Liu, Ronald P. Danis, Barbara A. Blodi Abstract Purpose: To compare retinal pigment epithelium (RPE) and retinal thickness assessments made with SDOCTin eyes with dry AMD and normal eyes. Methods: Eyes with intermediate AMD or worse in participants between 50 – 85 years of age were …
Amitha Domalpally, Ronald Danis, Emily Chew, Srinivas Sadda, Traci Clemons, Thomas R Friberg, and the AREDS2 Research Group Abstract Purpose: To characterize abnormalities in the peripheral retina using ultrawidefield (UWF) autofluorescence (AF) images in eyes with age related macular degeneration (AMD) Methods: UWF images (200 degrees) centered on the posterior pole as well as steered …
Jeong W. Pak, Amitha Domalpally, Dawn Myers, Xiufen Yang, Ashwini Narkar, Yijun Huang, and Ronald P. Danis Abstract Purpose: To characterize drusen morphology and retinal layer abnormalities by simple, ordinal description and to associate these features with drusen progression over one year on SD-OCT scans. Methods: Twenty two pairs of SD-OCT macular volume scans at …
Jane R. Armstrong, James White, Amitha Domalpally, Ronald P. Danis, Barbara Blodi, Qian Peng, Michael L. Klein, AREDS2 Research Group. Abstract Purpose: To assess retinal precursors of Geographic atrophy (GA) in digital images from the AREDS2 data set. Methods: The Age Related Eye Disease Study 2 (AREDS2) is a multi-center randomized trial of 4,200 participants …
Ronald P. Danis, Jane Armstrong, Qian Peng, Amitha Domalpally, Larry Hubbard, and the AREDS2 Research Group Abstract Purpose: The 11-step AREDS Severity Scale for age related macular degeneration (AMD) cross tabulates macular features from stereoscopic color photographs (AREDS Report no. 18) according to the risk of progression to advanced AMD. Two-step progression along this scale …
Qian Peng, Ronald P. Danis, Amitha Domalpally, Larry Hubbard, Jane Armstrong, and the AREDS2 Research Group Abstract Purpose: In the Age-Related Eye Disease Study 2 (AREDS2), a large multicenter clinical trial of nutritional supplements on the progression of age-related macular degeneration (AMD), we describe the rationale to migrate from the traditional multistep grading system (MS) …
Jane Armstrong, Ronald Danis, Matthew D. Davis , B. Zhang, L. –Y. Lee, Ronald Klein, Barbara E. Klein, Larry D. Hubbard Abstract Purpose: To analyze the presence of calcified drusen as a baseline risk factor for progression to advanced AMD, and to illustrate the course of such eyes, in the Age-Related Eye Diseases Study (AREDS). …
Jane Armstrong, Matthew D. Davis, R.E. Gangnon, L. –Y. Lee, Ronald Klein, Barbara E. Klein, R. C. Milton, F.L. Ferris, Larry D. Hubbard Abstract Purpose: To summarize the AREDS severity scale for age–related macular degeneration (AMD) and to present photographs of typical eyes from each level. Methods: AREDS enrolled persons without advanced AMD in at …