University of Wisconsin–Madison
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The Wisconsin Reading Center

Clinical trial imaging, grading, and quality assurance from a trusted academic partner.

The Wisconsin Reading Center (WRC), formerly the Fundus Photograph Reading Center, is a core image reading lab in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin–Madison. Since 1970, the WRC has provided high-quality, validated retinal image analysis for over 300 clinical trials. We support studies ranging from diabetic retinopathy to age-related macular degeneration (AMD), inherited retinal diseases, and more. Our work informs NIH-funded research, industry-sponsored trials, and innovations in imaging protocols.

Our Organization’s History, Structure, and Mission

WRC is part of the University of Wisconsin School of Medicine and Public Health. All WRC employees are university staff, and contracts are reviewed and approved through UW business and legal channels.

Founded to support landmark NIH trials in diabetic retinopathy, we have grown to support over 300 trials and multiple NIH consortia. WRC remains guided by our foundational values: intellectual honestyquality control, and innovation.

Our Experience By The Numbers

  • 315 ophthalmology clinical trials hosted
  • 3,180 total clinical sites served
  • 59 participating countries
  • 20,604 certified users
  • 57,298 total participants supported
  • 100,000+ images graded annually
  • 30 dedicated graders, many cross-trained
  • 12+ years average experience for color/angiography graders
  • 7+ years average experience for OCT graders
Bird's eye view of Lake Mendota and the UW-Madison campus.

Contact Us

The Wisconsin Reading Center
Tel: (608) 262-1334
Madison, WI